Audrey (Mila Kunis) and Morgan (Kate McKinnon), two thirty-something friends living in Los Angeles, find themselves at the center of an international conspiracy when Audrey's ex-boyfriend (Justin Theroux) shows up at their apartment to hide from a group of ruthless assassins who are chasing him.
Disbelieving and stunned, the two women will be forced to spring into action and transform into two expert spies.
They'll have to contend with the killers and a mysterious and charming British secret agent, all while trying to save the world... and their own skin.